You can control the number of approvers required for a requester. You can also control the number of approvers required for each access type: View Password, RDP, and SSH. This is configured in an access policy, which can then be assigned to a group when assigning Password Safe roles to the group.
Any of the approvers in the group can approve the request. If other subsequent approvers click the link, they will see that the request has already been approved. Other approvers can, however, override the approval and deny the request. If a request is denied by one approver, no approvers can subsequently override and approve. It is not possible to deny the request once the schedule window has actually begun.
For more information, please see Create a Group and Assign Roles.